Let’s Talk: A Conversation with Professor Caicun Zhou

September 17, 2026

Lung cancer care has undergone one of the most dramatic transformations in modern oncology, moving from a landscape defined by limited treatment options and poor prognoses to one shaped by precision biomarker testing, targeted therapy, immunotherapy, and now next-generation bispecific antibodies redefining the standard of care.

In this webcast, Professor Caicun Zhou, Director of Oncology Department at Shanghai East Hospital and Director of Tongji University Cancer Institute, and principle investigator of the HARMONi-2 clinical trial for Ivonescimab versus pembrolizumab in NSCLC, joins Christopher Ung, our Chief Scientific Business Officer, for an in-depth conversation on the evolution of lung cancer and China’s growing role in global oncology innovation.

 

Key topics discussed in this webcast:

CellCarta is excited to share this conversation between lung cancer treatment pioneer Professor Caicun Zhou and our Chief Scientific Business Officer Christopher Ung. We support clinical trials from discovery to translation and companion diagnostic development. If you are working on biomarker driven therapeutics or NSCLC, connect with our team to discover how we can help you accelerate your programs- from targeted genomic assays with rapid turn around times for genomic alterations (AGAs) to custom NGS assay development for your specific program needs.

 

About the Speakers:

Professor Caicun Zhou

Professor Caicun Zhou is the Director of Oncology Department at Shanghai East Hospital and Director of Tongji University Cancer Institute, and principle investigator of the HARMONi-2i clinical trial. He joined the IASLC Board of Directors in 2019 and currently serves as President of the organization, the first from mainland China. With more than 20 years of experience in clinical oncology, Professor Zhou has focused his research on early detection, molecular targeted therapy, anti-angiogenesis therapy, and immunotherapy in lung cancer. Professor Zhou has published over 200 articles in international peer-reviewed journals, including The Lancet Oncology, The Lancet Respiratory Medicine, Journal of Clinical Oncology, and Annals of Oncology, and has authored three books on lung cancer. In 2002, he worked as a visiting scientist at the MD Anderson Cancer Center. He studied medicine at NanTong Medical College, earned his Ph.D. at China Medical University, and served as a fellow at Tokyo National Chest Hospital.

Christopher Ung

Christopher Ung is CellCarta’s Chief Scientific Business Officer and has served in the companion diagnostics field since its inception. He is one of the original pioneers of the personalized medicine field. Mr. Ung currently leads the development and execution of CellCarta’s strategic and business initiatives, leveraging the company’s solid tumor and digital services.

Let’s Talk Webcasts

Our Webcast series features in-depth conversations with thought leaders in precision therapeutics. Join our speakers as they engage in insightful fireside chat-style discussions on a variety of topics in this dynamic space.

Subscribe to our newsletter to not miss our future Webcasts!

Let’s Talk: A Conversation with Professor Caicun Zhou

September 17, 2026

Lung cancer care has undergone one of the most dramatic transformations in modern oncology, moving from a landscape defined by limited treatment options and poor prognoses to one shaped by precision biomarker testing, targeted therapy, immunotherapy, and now next-generation bispecific antibodies redefining the standard of care.

In this webcast, Professor Caicun Zhou, Director of Oncology Department at Shanghai East Hospital and Director of Tongji University Cancer Institute, and principle investigator of the HARMONi-2 clinical trial for Ivonescimab versus pembrolizumab in NSCLC, joins Christopher Ung, our Chief Scientific Business Officer, for an in-depth conversation on the evolution of lung cancer and China’s growing role in global oncology innovation.

 

Key topics discussed in this webcast:

CellCarta is excited to share this conversation between lung cancer treatment pioneer Professor Caicun Zhou and our Chief Scientific Business Officer Christopher Ung. We support clinical trials from discovery to translation and companion diagnostic development. If you are working on biomarker driven therapeutics or NSCLC, connect with our team to discover how we can help you accelerate your programs- from targeted genomic assays with rapid turn around times for genomic alterations (AGAs) to custom NGS assay development for your specific program needs.

 

About the Speakers:

Professor Caicun Zhou

Professor Caicun Zhou is the Director of Oncology Department at Shanghai East Hospital and Director of Tongji University Cancer Institute, and principle investigator of the HARMONi-2i clinical trial. He joined the IASLC Board of Directors in 2019 and currently serves as President of the organization, the first from mainland China. With more than 20 years of experience in clinical oncology, Professor Zhou has focused his research on early detection, molecular targeted therapy, anti-angiogenesis therapy, and immunotherapy in lung cancer. Professor Zhou has published over 200 articles in international peer-reviewed journals, including The Lancet Oncology, The Lancet Respiratory Medicine, Journal of Clinical Oncology, and Annals of Oncology, and has authored three books on lung cancer. In 2002, he worked as a visiting scientist at the MD Anderson Cancer Center. He studied medicine at NanTong Medical College, earned his Ph.D. at China Medical University, and served as a fellow at Tokyo National Chest Hospital.

Christopher Ung

Christopher Ung is CellCarta’s Chief Scientific Business Officer and has served in the companion diagnostics field since its inception. He is one of the original pioneers of the personalized medicine field. Mr. Ung currently leads the development and execution of CellCarta’s strategic and business initiatives, leveraging the company’s solid tumor and digital services.

Let’s Talk Webcasts

Our Webcast series features in-depth conversations with thought leaders in precision therapeutics. Join our speakers as they engage in insightful fireside chat-style discussions on a variety of topics in this dynamic space.

Subscribe to our newsletter to not miss our future Webcasts!

George Demetri, MD and Charles Saywers, MD: Chats with Our Scientific Advisory Board

August 28, 2026

George Demetri, MD and Charles Saywers, MD, members of CellCarta's Scientific Advisory Board, join Christopher Ung, our Chief Scientific Business Officer, for a conversation on advancements in immunotherapies, treating solid tumors, and what's next for the field.

George Demetri, MD and Charles Saywers, MD: Chats with Our Scientific Advisory Board

August 28, 2026

George Demetri, MD and Charles Saywers, MD, members of CellCarta's Scientific Advisory Board, join Christopher Ung, our Chief Scientific Business Officer, for a conversation on advancements in immunotherapies, treating solid tumors, and what's next for the field.

Case Study: Delivering Clinical-Grade Interpretable Findings from Hyperplex Spatial Biology

July 17, 2026

The challenge: Hyperplex data eliminates inter-slide variability, but introduces it's own challenges

By reading dozens of markers from a single slide, spatial biology approaches minimize tissue use and remove slide-to-slide variability. But it comes with its own challenges: huge data volumes, and the requirement for stringent phenotyping consistency and analytical rigor to make accurate, actionable conclusions.

The platform: Built on the COMET

How the COMET works: an integrated staining and scanning system analyzing up to 40 markers on a single slide through iterative stain-image-elute cycles, built for the standardized, documented protocols clinical trial contexts demand.

The assay was developed and validated for accuracy, sensitivity, specificity, and cross-site concordance between CellCarta's labs in Lake Forest, California and Antwerp, Belgium.

The study: Complete responder vs non-responder dataset

In a 20-plex hyperplex analysis of tissue samples from patients with muscle-invasive bladder cancer treated with neo-adjuvant immunotherapy, CellCarta's clinical-grade COMET workflow highlighted distinct differences in immune composition, spatial proximity, and tissue organization between an immunotherapy responder and a non-responder, all from a single slide per patient.

  1. Phenotype composition how immune, stromal, and tumor proportions differed between the two cases
  2. Spatial distance, co-localization and niche analysis
  3. What it means for IO programs how tissue organization, not just cell counts, reflects response
  4. How we build global assays for comparable results, regardless of data collection location
  5. The clinical-grade, platform agnostic workflow that turns hyperplex image data into reliable, interpretable biological findings

From early-stage biotechs to established biopharma, understanding why some patients respond better than others is essential.

Read the full case study!

Case Study: Delivering Clinical-Grade Interpretable Findings from Hyperplex Spatial Biology

July 17, 2026

The challenge: Hyperplex data eliminates inter-slide variability, but introduces it's own challenges

By reading dozens of markers from a single slide, spatial biology approaches minimize tissue use and remove slide-to-slide variability. But it comes with its own challenges: huge data volumes, and the requirement for stringent phenotyping consistency and analytical rigor to make accurate, actionable conclusions.

The platform: Built on the COMET

How the COMET works: an integrated staining and scanning system analyzing up to 40 markers on a single slide through iterative stain-image-elute cycles, built for the standardized, documented protocols clinical trial contexts demand.

The assay was developed and validated for accuracy, sensitivity, specificity, and cross-site concordance between CellCarta's labs in Lake Forest, California and Antwerp, Belgium.

The study: Complete responder vs non-responder dataset

In a 20-plex hyperplex analysis of tissue samples from patients with muscle-invasive bladder cancer treated with neo-adjuvant immunotherapy, CellCarta's clinical-grade COMET workflow highlighted distinct differences in immune composition, spatial proximity, and tissue organization between an immunotherapy responder and a non-responder, all from a single slide per patient.

  1. Phenotype composition how immune, stromal, and tumor proportions differed between the two cases
  2. Spatial distance, co-localization and niche analysis
  3. What it means for IO programs how tissue organization, not just cell counts, reflects response
  4. How we build global assays for comparable results, regardless of data collection location
  5. The clinical-grade, platform agnostic workflow that turns hyperplex image data into reliable, interpretable biological findings

From early-stage biotechs to established biopharma, understanding why some patients respond better than others is essential.

Read the full case study!

Scaling Liquid Biopsy Biomarker Discovery: multi-center, Analytical Validation of high resolution ctDNA Profiling Using TSO500 ctDNA v2.0 on NovaSeq X Plus

April 20, 2026

Scaling Liquid Biopsy Biomarker Discovery: multi-center, Analytical Validation of high resolution ctDNA Profiling Using TSO500 ctDNA v2.0 on NovaSeq X Plus

Scaling Liquid Biopsy Biomarker Discovery: multi-center, Analytical Validation of high resolution ctDNA Profiling Using TSO500 ctDNA v2.0 on NovaSeq X Plus

April 20, 2026

Scaling Liquid Biopsy Biomarker Discovery: multi-center, Analytical Validation of high resolution ctDNA Profiling Using TSO500 ctDNA v2.0 on NovaSeq X Plus

Validation of an ultra-sensitive assay for biomarker testing in NSCLC patients as Clinical Trial Assay (CTA)

March 3, 2026

Validation of an ultra-sensitive assay for biomarker testing in NSCLC patients as Clinical Trial Assay (CTA)

Validation of an ultra-sensitive assay for biomarker testing in NSCLC patients as Clinical Trial Assay (CTA)

March 3, 2026

Validation of an ultra-sensitive assay for biomarker testing in NSCLC patients as Clinical Trial Assay (CTA)