Peripheral blood mononuclear cells (PBMCs) include lymphocytes and monocytes, the primary cell populations used in immune monitoring and biomarker studies. PBMC processing involves isolating these cells from whole blood using density gradient centrifugation.
\nAt CellCarta,optimized isolation protocols consistently achieve over 90% PBMC viability,protecting cell integrity for downstream analysis and cryopreservation. Reliable PBMC processing services at this standard are critical for producing reproducible data across multi-center clinical trials.
"},{"faq_question":"How quickly can PBMC processing occur? ","faq_answer":"CellCarta offers same-day PBMC processing services. Minimizing time between blood collection and processing is crucial for maintaining optimal PBMC quality as delays can ultimately compromise cell viability,recovery, and downstream assay performance. Our sample management and logistics team is accountable for the full process,from collection and transportation to processing and storage,ensuring each sample reaches our laboratories and is handled without unnecessary hold time.
"},{"faq_question":"Which tube types do you accept for PBMC processing? ","faq_answer":"CellCarta isolates PBMCs from a range of collection tube types and anticoagulants,including sodium heparin,EDTA,ACD,and CPT tubes. If your study protocol calls for a specific collection tube,our team will confirm compatibility and adjust handling procedures accordingly. This flexibility allows CellCarta's PBMC processing services to align with your existing study design without requiring protocol changes from your clinical sites.
"},{"faq_question":"Can your team perform flow cytometry on isolated PBMCs? ","faq_answer":"Yes. CellCarta's PBMC processing services connect directly to our flow cytometry platform. Both conventional and spectral flow cytometry are available for the analysis of isolated PBMCs, including off-the-shelf panels such as ICS,T-cell and B-cell profile assays,and the spectral PBMC assay,which are pre-validated across our global sites. Customized panels are also available for exploratory and clinical trial studies. This integrated path from PBMC isolation to immunophenotyping data allows your team to work with a single partner from sample to result.
"},{"faq_question":"What downstream analysis is available for PBMCs? ","faq_answer":"From your fresh or cryopreserved PBMC samples,several of our bioanalytical services can be employed to extract key information regarding therapeutic development and patient monitoring. This includes mass spectrometry,flow cytometry, singleplex and multiplex immunoassays,and genomics analysis,including the 10X Genomics Chromium X platform.
"}]}#-supreme-cellcarta-featured-resources-46-683{cards-data:[{"image_url":"https://cellcarta.com/wp-content/uploads/2023/10/CellCarta_Logistics_Brochure_2023-10-12_SS.png","card_type":"","date":"Oct 16,2023","reading_time":"","title":"Sample Logistics & Kitting Solutions","description":"","url":"/science-hub/sample-logistics-kitting-solutions/"},{"image_url":"https://cellcarta.com/wp-content/uploads/2025/10/SITC-Poster.png","card_type":"","date":"Oct 30,2025","reading_time":"","title":"Combining high-plex proteomics with single-cell transcriptomics for deep characterization of antigen-specific T cell responses","description":"","url":"/science-hub/high-plex-proteomics-single-cell-transcriptomics-tcell-responses/"},{"image_url":"https://cellcarta.com/wp-content/uploads/2026/07/Cellcarta-Tagline_logo.jpg","image_alt":"","card_type":"","date":"Feb 17,2025","reading_time":"","title":"A Phase I Study of FHD-609,a Heterobifunctional Degrader of Bromodomain-Containing Protein 9,in Patients with Advanced Synovial Sarcoma or SMARCB1-Deficient Tumors","description":"","url":"https://pubmed.ncbi.nlm.nih.gov/39660994/","link_target":"_blank"}]}#-supreme-cellcarta-service-blocks-45-176{blocks-data:[{"image":"https://cellcarta.com/wp-content/uploads/2026/06/PBMC-Processing-Service-19-2.jpg","image_alt":"","title":"Immune Monitoring","description":"Advanced cell-based and immunoassays to support immune profiling in complex clinical studies. ","button_text":"Discover","button_url":"/capabilities/immune-monitoring/","button_target":"_self"},{"image":"/wp-content/uploads/2026/06/PBMC-Processing-service-421.jpg","image_alt":"","title":"Clinical Site Training","description":"Personalized training for clinical sites on sample collection,preparation,and shipment. ","button_text":"Discover","button_url":"/clinical-trial-services/sample-logistics/clinical-site-training/","button_target":"_self"},{"image":"https://cellcarta.com/wp-content/uploads/2026/08/CellCarta-188-5-scaled.jpg","image_alt":"","title":"Sample Management","description":"Start-to-finish oversight with real-time tracking and direct shipment to bioanalytical labs. ","button_text":"Discover","button_url":"/clinical-trial-services/sample-logistics/sample-management/","button_target":"_self"}]}#-supreme-cellcarta-tab-content-11-144{tabs-data:[{"tab_title":"Isolation Techniques ","content_title":"","content_body":"Our optimized isolation techniques consistently achieve over 90% PBMC viability from whole blood.
\nBased on your study’s specifications,we can isolate PBMCs from a variety of collection tubes and anticoagulants,such as sodium heparin,CPT tubes,EDTA,ACD,and more.
\nStandardized SOPs applied at every global PBMC lab,ensuring that results are consistent across sites. This gives your team a reliable foundation for downstream biomarker analysis.
","tab_image":"https://cellcarta.com/wp-content/uploads/2026/07/CellCarta_-52-2-3-scaled.jpg","image_alt":""},{"tab_title":"Sample Storage","content_title":"","content_body":"On-site biorepository services are available across CellCarta's global PBMC processing locations,providing secure,condition-controlled storage for isolated and cryopreserved samples.
\nWhether you need short-term storage support or long-term archive management,our facilities maintain your samples under optimal conditions to preserve integrity throughout the study’s lifecycle.
","tab_image":"https://cellcarta.com/wp-content/uploads/2026/06/Reliable-Tab-232.jpg","image_alt":""},{"tab_title":"Advanced Analysis ","content_title":"","content_body":"Follow up your PBMC isolation with CellCarta's breadth of services for downstream analysis,including flow cytometry, mass spectrometry, and ELISpot.
\nFor flow cytometry and mass cytometry,off-the-shelf (OTS) panels,including ICS,T cell and B cell profiling panels,are pre-validated at our sites,providing the fastest runway to analysis from PBMC samples.
\nCustomized panels are available to support therapeutic development studies at any stage.
","tab_image":"/wp-content/uploads/2026/06/PBMC-Services-tabs-3.jpg","image_alt":"Scientist operating a flow cytometry instrument."}]}