#-supreme-cellcarta-differentiators-5-698{items-data:[{"text":"Cutting-Edge Platform"},{"text":"Analytical Capabilities"},{"text":"Global Execution"},{"text":"Clinical Implementation"},{"text":"Immune Expertise"}]}#-supreme-cellcarta-faq-9-698{items-data:[{"faq_question":"What is the basophil activation test?","faq_answer":"<p>The basophil activation test is a clinical and exploratory assay performed on whole blood samples using flow cytometry. It specifically investigates degranulation markers,which can be used to measure allergy severity,monitor tolerance towards allergens,and observe clinical response to immunomodulatory treatments over time.</p>\n<p>At CellCarta,we use the FlowCAST&trade;test in whole blood samples,identifying basophils as SSC<sup>LOW</sup> and CCR3+,while using CD63 as a reliable activation marker.</p>"},{"faq_question":"Can BAT be used as a pharmacodynamic marker?","faq_answer":"<p>Yes. In addition to its use in allergy clinical trials,the basophil activation test can serve as a surrogate pharmacodynamic (PD) marker to monitor the effect of compounds targeting the degranulation pathway and protein tyrosine kinases such as SYK. This makes the basophil test applicable across immunology and oncology drug development programs targeting these pathways.</p>"},{"faq_question":"What flow cytometry platform does CellCarta use for BAT?","faq_answer":"<p>CellCarta uses the FlowCAST&trade;kit combined with its flow cytometry platforms to investigate basophil activation. Our basophil lab test define basophils as SSC<sup>LOW</sup> and CCR3+ and the activation marker CD63 is used to investigate degranulation.</p>"}]}#-supreme-cellcarta-service-blocks-6-698{blocks-data:[{"image":"https://cellcarta.com/wp-content/uploads/2026/08/CellCarta_-59-1-scaled.jpg","image_alt":"Cellular phenotyping flow cytometry panel","title":"Cellular Phenotyping","description":"Characterize complex immune cell subsets using off-the-shelf or fully customized panels.","button_text":"Discover","button_url":"/capabilities/immune-monitoring/cell-phenotyping/","button_target":"_self"},{"image":"https://cellcarta.com/wp-content/uploads/2026/06/Intracellular-Cytokine-Staining-hero-68.jpg","image_alt":"Intracellular cytokine staining assay","title":"Intracellular Cytokine Staining","description":"Detect cytokine production at the single-cell level to profile immune function.","button_text":"Discover","button_url":"/capabilities/immune-monitoring/intracellular-cytokine-staining/","button_target":"_self"},{"image":"https://cellcarta.com/wp-content/uploads/2026/07/CellCarta_-44-scaled.jpg","image_alt":"CellEngine flow cytometry software dashboard","title":"CellEngine® Software","description":"Advanced flow cytometry analysis and data visualization with incredible speed.","button_text":"Discover","button_url":"/clinical-trial-services/ai-data-analytics/cellengine-cytometry-software/","button_target":"_self"}]}