Multiplex Assay for Measuring 45 Cytokines in NSCLC Plasma
November 7, 2023
Anne Jang, Daniel Feingold, Mark Watson, Gwenaël Pottiez, Rudolf Guilbaud and Nicholas Dupuis
CellCarta’s poster showcases the analytical performance of a 45-analyte panel using proximity extension assay (PEA) to measure cytokines in plasma from subjects with non-small cell lung cancer (NSCLC).
The study highlights the panel’s sensitivity and precision, demonstrating its ability to detect cytokine levels and identify differentially expressed cytokines between normal and NSCLC samples. The use of this multiplex panel provides insights into cytokine profiles, aiding in the characterization of pharmacodynamic and mechanistic effects of investigational therapies.
Contact us for more insights on advanced cytokine measurement techniques in cancer research.
View the full poster:
Analytical characterization of a multiplex proximity extension assay panel measuring 45 cytokines in plasma from subjects with NSCLC
As presented at SITC 2023 and AACR 2023
Multiplex Assay for Measuring 45 Cytokines in NSCLC Plasma
November 7, 2023
Anne Jang, Daniel Feingold, Mark Watson, Gwenaël Pottiez, Rudolf Guilbaud and Nicholas Dupuis
CellCarta’s poster showcases the analytical performance of a 45-analyte panel using proximity extension assay (PEA) to measure cytokines in plasma from subjects with non-small cell lung cancer (NSCLC).
The study highlights the panel’s sensitivity and precision, demonstrating its ability to detect cytokine levels and identify differentially expressed cytokines between normal and NSCLC samples. The use of this multiplex panel provides insights into cytokine profiles, aiding in the characterization of pharmacodynamic and mechanistic effects of investigational therapies.
Contact us for more insights on advanced cytokine measurement techniques in cancer research.
View the full poster:
Analytical characterization of a multiplex proximity extension assay panel measuring 45 cytokines in plasma from subjects with NSCLC
As presented at SITC 2023 and AACR 2023
Comparative Analysis of Digital Pathology Whole Slide Scanners
October 24, 2023
Wijendra Senarathne, Patrick Reese, Ellen Sluydts, James Thompson
CellCarta’s poster compares the performance of different digital pathology whole slide scanners (WSI) to improve standardization in digital pathology.
The study evaluates the image quality, color accuracy, and reliability of various scanners using a standardized set of pathological samples. It highlights the strengths and weaknesses of each scanner, providing guidance for pathologists and researchers in selecting the most appropriate WSI format for their needs. The inclusion of AI-driven algorithms for marker detection, such as PD-L1, demonstrates the potential for automation and improved diagnostic accuracy in digital pathology.
For more insights on advanced digital pathology solutions and scanner contact us today
View the full poster:
Seeing the Whole Picture: A Comparative Analysis of Digital Pathology Whole Slide Scanners
Comparative Analysis of Digital Pathology Whole Slide Scanners
October 24, 2023
Wijendra Senarathne, Patrick Reese, Ellen Sluydts, James Thompson
CellCarta’s poster compares the performance of different digital pathology whole slide scanners (WSI) to improve standardization in digital pathology.
The study evaluates the image quality, color accuracy, and reliability of various scanners using a standardized set of pathological samples. It highlights the strengths and weaknesses of each scanner, providing guidance for pathologists and researchers in selecting the most appropriate WSI format for their needs. The inclusion of AI-driven algorithms for marker detection, such as PD-L1, demonstrates the potential for automation and improved diagnostic accuracy in digital pathology.
For more insights on advanced digital pathology solutions and scanner contact us today
View the full poster:
Seeing the Whole Picture: A Comparative Analysis of Digital Pathology Whole Slide Scanners
CellEngine Auto-Gate: Accurate Gating in COVID Study
May 22, 2023
Anita L. Ray, Susan Reynolds, Zach Bjornson, Martin Tolstrup, Angela M. Cheung, Eustache Paramithiotis
CellCarta’s poster demonstrates the effectiveness of CellEngine’s automatic gate adjustment tool in cytometry analysis for a COVID-19 longitudinal clinical study. The tool uses a machine-learning algorithm trained on manually gated samples to automatically gate large datasets, significantly reducing analysis time while maintaining accuracy.
The study focused on two markers, CCR5 and perforin, known for high variability, and showed that the tool produced results highly similar to manual gating, with a time reduction of 69.3% for perforin and 88.5% for CCR5
View the full poster:
CellEngine’s automatic gate adjustment tool quickly and accurately recapitulates manual gating: assessment in a COVID longitudinal clinical study
As presented in CYTO2023
Autogating
- Closely correlates with manual gating
- Reduces analysis time by 69% to 89%
- Adjusts gates for thousands of files in seconds
- Full deterministic operation based on a few manually gated files
CellEngine Auto-Gate: Accurate Gating in COVID Study
May 22, 2023
Anita L. Ray, Susan Reynolds, Zach Bjornson, Martin Tolstrup, Angela M. Cheung, Eustache Paramithiotis
CellCarta’s poster demonstrates the effectiveness of CellEngine’s automatic gate adjustment tool in cytometry analysis for a COVID-19 longitudinal clinical study. The tool uses a machine-learning algorithm trained on manually gated samples to automatically gate large datasets, significantly reducing analysis time while maintaining accuracy.
The study focused on two markers, CCR5 and perforin, known for high variability, and showed that the tool produced results highly similar to manual gating, with a time reduction of 69.3% for perforin and 88.5% for CCR5
View the full poster:
CellEngine’s automatic gate adjustment tool quickly and accurately recapitulates manual gating: assessment in a COVID longitudinal clinical study
As presented in CYTO2023
Autogating
- Closely correlates with manual gating
- Reduces analysis time by 69% to 89%
- Adjusts gates for thousands of files in seconds
- Full deterministic operation based on a few manually gated files
sBCMA Plasma Quantification via Hybrid Mass Spectrometry
July 27, 2021
Luca Genovesi, Michael Schirm, Gwenaël Pottiez, Rudolf Guilbaud and Lorella Di Donato
CellCarta’s poster presents a high-throughput hybrid immunoaffinity LC-MRM based method for quantifying soluble BCMA (sBCMA) in human plasma.
The study demonstrates that sBCMA, a marker for multiple myeloma, can be precisely measured using this method, which overcomes interferences from ligands and therapeutic antibodies. The assay shows high sensitivity, a broad linear range, and robustness against interferences, making it suitable for clinical studies and monitoring treatment response in multiple myeloma patients
Quantification of sBCMA in Human Plasma using a High-ThroughputHybrid IP-MRM Based Mass Spectrometry Workflow, As presented at ASMS 2022
sBCMA Plasma Quantification via Hybrid Mass Spectrometry
July 27, 2021
Luca Genovesi, Michael Schirm, Gwenaël Pottiez, Rudolf Guilbaud and Lorella Di Donato
CellCarta’s poster presents a high-throughput hybrid immunoaffinity LC-MRM based method for quantifying soluble BCMA (sBCMA) in human plasma.
The study demonstrates that sBCMA, a marker for multiple myeloma, can be precisely measured using this method, which overcomes interferences from ligands and therapeutic antibodies. The assay shows high sensitivity, a broad linear range, and robustness against interferences, making it suitable for clinical studies and monitoring treatment response in multiple myeloma patients
Quantification of sBCMA in Human Plasma using a High-ThroughputHybrid IP-MRM Based Mass Spectrometry Workflow, As presented at ASMS 2022
