October 13, 2023
CellCarta’s poster presents a quantitative mass spectrometry workflow designed for the highly multiplexed measurement of immunomodulatory proteins to support immunotherapy clinical trials.
The workflow utilizes immuno-MRM assay panels to quantify up to 113 proteins with high sensitivity and precision, providing valuable data on immune-related biomarkers. This approach enhances the understanding of drug responses and mechanisms of action, crucial for developing new immunotherapies and combination treatments.
The method involves the use of stable-isotope-labeled peptides and immunoaffinity capture, followed by LC-MRM analysis for accurate protein quantification.
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View the full poster:
As presented at SITC 2023 AND EORTC 2023
