CDx
Contact Us

Ella™: Multiplexing ELISA

A next-generation, automated, benchtop multiplexing ELISA system that delivers high-speed precision with minimal user input.

Connect with Our Experts
Scientist operating Ella™ automated ELISA multiplexing system

Small Sample, Large Return

CellCarta can implement Ella™ by into your study, enabling high-throughput, high-speed analysis without sacrificing accuracy or precision.

Ella™ is a fully automated platform that uses the configurable, validated, and highly sensitive Simple Plex cartridges, allowing researchers to simultaneously save time and boost productivity, all while receiving key insights regarding your clinical samples.

Key Features of Ella™

Ella™ partners simplicity with precision for high performance ELISA multiplexing.

Stringent control of assay parameters combined with validated, pre-configured ELISA cartridges ensures accurate and reliable biomarker detection.

Ella™ autonomously manages volumes, flow rates, and flow patterns, achieving exceptional reproducibility and sensitivity. Notably, we offer the single plex ultra sensitivity assay, which can achieve a sensitivity below 1 pg/mL.

Ella™ can process up to 72 samples and 8 analytes simultaneously, generating up to 256 result readouts per run using the Simple Plex Cartridges.

Key features of the cartridges include:

  • Assay menu of >250 diverse targets
  • Four parallel channels that eliminate cross-reactivity
  • Triplicate results per analyte for increased reliability
  • Controlled sample inlets that reduce pipetting error
  • Sub-picogram sensitivity with up to 4 logs of dynamic range

With 10–15 minutes of preparation and up to 75 minutes of run time, Ella™ can deliver results in under 90 minutes, allowing your team to rapidly receive crucial, reliable results.

Ella™ assays have been validated for a variety of clinical sample types, including PBMCs, serum, and whole blood, across multiple species: human, mice, rat, and non-human primates.

Simple Plex cartridges are fully configurable to support your program’s requirements and can accommodate single analyte, multiple analyte, and multiplexed assays. Ella™ also accommodates 48-Digoxigenin cartridges that leverage user-defined reagents for custom assay development.

For clinical studies where patient sample availability is limited, that is no problem for Ella™. This multiplexing ELISA platform requires only 25 µL of sample per run, allowing your research team to maximize data output without drawing on additional or repeat samples.

Ella™ partners simplicity with precision for high performance ELISA multiplexing.

Stringent control of assay parameters combined with validated, pre-configured ELISA cartridges ensures accurate and reliable biomarker detection.

Ella™ autonomously manages volumes, flow rates, and flow patterns, achieving exceptional reproducibility and sensitivity. Notably, we offer the single plex ultra sensitivity assay, which can achieve a sensitivity below 1 pg/mL.

Scientist reviewing Ella™ high-performance ELISA multiplexing results

Ella™ can process up to 72 samples and 8 analytes simultaneously, generating up to 256 result readouts per run using the Simple Plex Cartridges.

Key features of the cartridges include:

  • Assay menu of >250 diverse targets
  • Four parallel channels that eliminate cross-reactivity
  • Triplicate results per analyte for increased reliability
  • Controlled sample inlets that reduce pipetting error
  • Sub-picogram sensitivity with up to 4 logs of dynamic range
Scientist loading Simple Plex cartridge into Ella™ multiplexing system

With 10–15 minutes of preparation and up to 75 minutes of run time, Ella™ can deliver results in under 90 minutes, allowing your team to rapidly receive crucial, reliable results.

Laboratory corridor showing rapid turnaround workflow for Ella™ assays

Ella™ assays have been validated for a variety of clinical sample types, including PBMCs, serum, and whole blood, across multiple species: human, mice, rat, and non-human primates.

Simple Plex cartridges are fully configurable to support your program’s requirements and can accommodate single analyte, multiple analyte, and multiplexed assays. Ella™ also accommodates 48-Digoxigenin cartridges that leverage user-defined reagents for custom assay development.

Scientist operating flexible Ella™ platform for multiple sample types

For clinical studies where patient sample availability is limited, that is no problem for Ella™. This multiplexing ELISA platform requires only 25 µL of sample per run, allowing your research team to maximize data output without drawing on additional or repeat samples.

Scientist preparing low-volume clinical sample for Ella™ analysis
Scientist reviewing Ella™ clinical application data in a laboratory

Clinical Application

CellCarta has extensive experience implementing Ella™ into clinical trials at multiple stages of development. This includes cytokine, chemokine, and soluble biomarker measurements for therapy development, patient monitoring, and safety assessments. Our team can discuss the best way to incorporate Ella™ into your study.

Why CellCarta

The fully automated Ella™ platform ensures excellent reproducibility and sensitivity with every run.

Sub-Picogram Sensitivity

Multiplex Capabilities

Low Sample Volume Needed

Incredible Speed

Highly Configurable

Simplify your ELISA multiplexing workflow

CellCarta can discuss your biomarker and immune monitoring platform in further detail and help incorporate Ella™ into your program.

CellCarta scientist incorporating Ella™ into clinical biomarker program

Frequently Asked Questions

Ella™ is a next-generation, automated, benchtop ELISA multiplexing system that uses fully configurable, validated, and highly sensitive Simple Plex cartridges from Bio-Techne. Without operator intervention, Ella™ precisely controls the assay by managing volumes, flow rates, and flow patterns, ensuring accurate and consistent biomarker detection through stringent control of time, volume, and temperature parameters.

Ella™ has superior multiplexing capabilities, processing up to 72 samples and 8 analytes simultaneously and generating up to 256 result readouts per run. The Simple Plex cartridges support single analyte, multiple analyte, and multiplexed assay formats. Furthermore, the cartridges’ assay menu includes more than 250 validated targets, spanning pre-clinical research through bio-therapeutic manufacturing applications.

Ella™ requires 10–15 minutes of preparation, followed by up to 75 minutes of automated run time. This translates to a result turnaround time of under 90 minutes, delivering rapid data output without compromising accuracy or requiring continuous operator oversight.

Ella™ requires only 25 µL of sample volume per run. This low input requirement is particularly relevant for clinical research programs where patient sample availability is limited, enabling more data to be generated from fewer samples.

Ella™ is a highly sensitive platform for analyte detection, with sub-picogram detection and up to 4 logs of dynamic range available via the Simple Plex cartridges. For example, the single-plex ultra sensitivity assay achieves sensitivity below 1 pg/mL. Additionally, the cartridges’ microfluidic circuit architecture and housed in glass nanoreactors (GNRs) with four parallel channels eliminates cross-reactivity and provides triplicate results per analyte, increasing data reliability.