Combined metal-isotope-tagged antibodies and time-of-flight detection to characterize up to 50 markers simultaneously for high-content cytometric analysis.
CyTOF mass cytometry represents a significant advancement in single-cell analysis that greatly increases the depth of immune monitoring.
CellCarta supports the full CyTOF workflow from custom panel design and reagent conjugation to sample staining, acquisition, and data analysis. Whether you are running an exploratory biomarker program or a regulated clinical study, our integrated scientific team can guide your program and collaborate to optimize your immune monitoring workflow.
Our team can support custom panel design and antibody conjugation, where we can readily adapt to your study’s parameters and build a CyTOF panel starting from purified or unconjugated antibodies, as well as custom reagents.
Whether your panel includes antibodies specific to your application, markers that are not currently available, or antibodies for different animal species, we will help you select the right antibody clones and conjugation conditions.
Our end-to-end CyTOF workflow supports a wide range of sample types, whether fresh or frozen, including:
To simplify your clinical trial’s proceedings, we also offer in-house sample procurement, preparation, stimulation, and stabilization if needed.
CellCarta’s integrated bioinformatics teams harness the combined power of CellEngine®, our proprietary cloud-based flow cytometry software, and Spotfire analytics to interpret high-dimensional CyTOF data. These tools enable our team to move rapidly from millions of cellular events to actionable visualizations of compound activity across hundreds of readouts. Thus, your study receives key biological insights to help advance your program and inform crucial decisions.
CellCarta delivers CyTOF mass cytometry in a GCLP environment, supporting both preclinical exploratory programs and regulated clinical studies.
For every step of our workflow, rigorous quality standards are applied to ensure results are reproducible, quantifiable, and suitable for regulatory submission.
For studies that require large-scale sample processing and highly complex phenotyping suitable for clinical trials, CyTOF is the platform to depend on. CyTOF’s multiplex and highplex capabilities allow for the simultaneous assessment of 30 to 50 markers, allowing your study to proceed without delay.
Our team can support custom panel design and antibody conjugation, where we can readily adapt to your study’s parameters and build a CyTOF panel starting from purified or unconjugated antibodies, as well as custom reagents.
Whether your panel includes antibodies specific to your application, markers that are not currently available, or antibodies for different animal species, we will help you select the right antibody clones and conjugation conditions.
Our end-to-end CyTOF workflow supports a wide range of sample types, whether fresh or frozen, including:
To simplify your clinical trial’s proceedings, we also offer in-house sample procurement, preparation, stimulation, and stabilization if needed.
CellCarta’s integrated bioinformatics teams harness the combined power of CellEngine®, our proprietary cloud-based flow cytometry software, and Spotfire analytics to interpret high-dimensional CyTOF data. These tools enable our team to move rapidly from millions of cellular events to actionable visualizations of compound activity across hundreds of readouts. Thus, your study receives key biological insights to help advance your program and inform crucial decisions.
CellCarta delivers CyTOF mass cytometry in a GCLP environment, supporting both preclinical exploratory programs and regulated clinical studies.
For every step of our workflow, rigorous quality standards are applied to ensure results are reproducible, quantifiable, and suitable for regulatory submission.
For studies that require large-scale sample processing and highly complex phenotyping suitable for clinical trials, CyTOF is the platform to depend on. CyTOF’s multiplex and highplex capabilities allow for the simultaneous assessment of 30 to 50 markers, allowing your study to proceed without delay.
CyTOF mass cytometry supports highly multiplexed single-cell analyses across a wide range of immune cell populations. CellCarta applies this platform to simultaneously probe multiple signaling pathways and identify functional, polyclonal activation of immune cell subsets in clinical samples.
CellEngine’s CyTOF tool was developed with Standard BioTools to automatically identify live, single cells and generate QC reports in seconds. This allows users to move directly into clustering, dimensionality reduction, and advanced visualizations, suited to the scale of deep CyTOF datasets.
Integrated CyTOF services to receive reliable, quality biomarker and immune insights.
Single-Cell Depth
Validated GCLP Workflow
Advanced Data Analysis
Custom Panel Design
Multiplex Capabilities
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CyTOF mass cytometry combines metal-isotope-tagged antibodies with time-of-flight detection to enable high-content single-cell analysis. It allows simultaneous evaluation of up to 50 markers per cell with little to no signal overlap, providing greater depth of immune monitoring than standard fluorescence cytometry, especially for complex phenotyping of rare cell subsets.
CellCarta’s CyTOF platform is validated for a wide range of sample types, whether fresh or frozen, including PBMCs, whole blood, bone marrow aspirate, and dissociated tumors and tissue. Our team optimizes staining conditions and sample handling protocols to ensure maximum cell recovery across all supported sample types, including complex clinical matrices.
Yes. As commercially available CyTOF antibodies can be rather limited, CellCarta offers custom antibody conjugation starting from purified, unconjugated antibodies or custom reagents. The team provides expert guidance in selecting the right antibody clones and conjugation conditions, and supports antibodies for unique applications, unavailable markers, and multiple animal species.
Yes. CellCarta delivers CyTOF mass cytometry services in a GCLP (Good Clinical Laboratory Practice) environment, with validated staining conditions, optimized sample handling, and rigorous quality controls, supporting both exploratory research programs and regulated clinical sample analysis.
CellCarta uses CellEngine®, our proprietary cloud-based flow cytometry software, alongside Spotfire analytics software. These tools enable the team to move rapidly from millions of cellular events to actionable visualizations of compound activity across hundreds of readouts.
