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PBMC Processing Services

End-to-end PBMC processing that protects clinical sample integrity and viability from collection to analysis.

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PBMC processing services

Expert-level Support

CellCarta specializes in high-quality Peripheral Blood Mononuclear Cells (PBMC) processing services, with precise handling at every stage. Backed by our state-of-the-art facilities and highly trained staff, we can provide same-day sample processing for optimal PBMC quality.

Our PBMC lab network spans Australia, Belgium, China, and North America, with key partners in South Korea and Japan. Our labs operate under the same standardized SOPs to deliver consistent, quality results across your global program.

PBMC Isolation Tailored for You

Our optimized isolation techniques consistently achieve over 90% PBMC viability from whole blood.

Based on your study’s specifications, we can isolate PBMCs from a variety of collection tubes and anticoagulants, such as sodium heparin, CPT tubes, EDTA, ACD, and more.

Standardized SOPs applied at every global PBMC lab, ensuring that results are consistent across sites. This gives your team a reliable foundation for downstream biomarker analysis.

On-site biorepository services are available across CellCarta's global PBMC processing locations, providing secure, condition-controlled storage for isolated and cryopreserved samples.

Whether you need short-term storage support or long-term archive management, our facilities maintain your samples under optimal conditions to preserve integrity throughout the study’s lifecycle.

Follow up your PBMC isolation with CellCarta's breadth of services for downstream analysis, including flow cytometrymass spectrometry, and ELISpot. 

For flow cytometry and mass cytometry, off-the-shelf (OTS) panels, including ICS, T cell and B cell profiling panels, are pre-validated at our sites, providing the fastest runway to analysis from PBMC samples.

Customized panels are available to support therapeutic development studies at any stage.  

Our optimized isolation techniques consistently achieve over 90% PBMC viability from whole blood.

Based on your study’s specifications, we can isolate PBMCs from a variety of collection tubes and anticoagulants, such as sodium heparin, CPT tubes, EDTA, ACD, and more.

Standardized SOPs applied at every global PBMC lab, ensuring that results are consistent across sites. This gives your team a reliable foundation for downstream biomarker analysis.

Scientist processing a sample at the laboratory bench.

On-site biorepository services are available across CellCarta's global PBMC processing locations, providing secure, condition-controlled storage for isolated and cryopreserved samples.

Whether you need short-term storage support or long-term archive management, our facilities maintain your samples under optimal conditions to preserve integrity throughout the study’s lifecycle.

Scientist handling samples at a -80 degree celsius freezer.

Follow up your PBMC isolation with CellCarta's breadth of services for downstream analysis, including flow cytometrymass spectrometry, and ELISpot. 

For flow cytometry and mass cytometry, off-the-shelf (OTS) panels, including ICS, T cell and B cell profiling panels, are pre-validated at our sites, providing the fastest runway to analysis from PBMC samples.

Customized panels are available to support therapeutic development studies at any stage.  

Scientist operating a flow cytometry instrument.
Scientist packing a CellCarta sample box.

Logistics Services

CellCarta sample logistic services can support the full therapeutic development journey, from blood collection and transportation to processing, analysis and storage. Our logistics team ensures chain-of-custody integrity at every step, providing custom solutions tailored to your requirements.

Case study

Spectral PBMC Assay

CellCarta designed a spectral flow cytometry panel for PBMC samples using a modular approach, allowing for streamlined assay validation when interchangeable markers are needed. This approach de-risks and accelerates the panel design phase, which is often a major obstacle during custom development.

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Why CellCarta

Your samples require consistent handling, scientific precision, and a global partner you can count on.

Optimal Recovery and Viability

Integrated Downstream Analysis

Global PBMC Lab Network

Same-Day Processing

End-to-End Sample Handling

Ready to Start Your PBMC Study?

CellCarta's global PBMC processing services are built for clinical programs that require precision, reproducibility, and accountability throughout.

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Frequently Asked Questions

Peripheral blood mononuclear cells (PBMCs) include lymphocytes and monocytes, the primary cell populations used in immune monitoring and biomarker studies. PBMC processing involves isolating these cells from whole blood using density gradient centrifugation.  

At CellCarta, optimized isolation protocols consistently achieve over 90% PBMC viability, protecting cell integrity for downstream analysis and cryopreservation. Reliable PBMC processing services at this standard are critical for producing reproducible data across multi-center clinical trials.

CellCarta offers same-day PBMC processing services. Minimizing time between blood collection and processing is crucial for maintaining optimal PBMC quality as delays can ultimately compromise cell viability, recovery, and downstream assay performance. Our sample management and logistics team is accountable for the full process, from collection and transportation to processing and storage, ensuring each sample reaches our laboratories and is handled without unnecessary hold time. 

CellCarta isolates PBMCs from a range of collection tube types and anticoagulants, including sodium heparin, EDTA, ACD, and CPT tubes. If your study protocol calls for a specific collection tube, our team will confirm compatibility and adjust handling procedures accordingly. This flexibility allows CellCarta's PBMC processing services to align with your existing study design without requiring protocol changes from your clinical sites.

Yes. CellCarta's PBMC processing services connect directly to our flow cytometry platform. Both conventional and spectral flow cytometry are available for the analysis of isolated PBMCsincluding off-the-shelf panels such as ICS, T-cell and B-cell profile assays, and the spectral PBMC assay, which are pre-validated across our global sites. Customized panels are also available for exploratory and clinical trial studies. This integrated path from PBMC isolation to immunophenotyping data allows your team to work with a single partner from sample to result. 

From your fresh or cryopreserved PBMC samples, several of our bioanalytical services can be employed to extract key information regarding therapeutic development and patient monitoring. This includes mass spectrometry, flow cytometrysingleplex and multiplex immunoassays, and genomics analysis, including the 10X Genomics Chromium X platform.