As a first adopter of digital whole slide high-resolution image capture and with nearly two decades of operations, we have resolved and pioneered multiple imaging and image analysis methodologies that are ideal for clinical trial deployment. All our services are guided by carefully optimized and rigorously documented procedures.
Key services include:
Each slide is digitally captured in high-resolution, whole-slide format and retained on our image servers. The larger part of the evaluation and scoring is performed by our team of trained pathologists and imaging scientists. Image scanning and analysis for clinical trials is performed in a CLIA-certified, CAP accredited laboratory.
At CellCarta, we use industry-standard scanning technology, like fluorescent and brightfield scanners from 3DHistech, Akoya, BioView, Leica Biosystems (Aperio®), Roche/Ventana, and Zeiss to enable high throughput, high resolution imaging with a fast turnaround time.
Whole slide scanning is a strategic solution for digital image archiving, image analysis, and sharing of staining results. We can provide whole-slide scanning as part of our end-to-end digital pathology services, or as a stand-alone service for your digitization programs.
Our broad portfolio of image analysis tools such as Reveal Bio’s imageDx™, Indica Labs’ HALO®, Visiopharm®, and Akoya’s inForm® help us capture the valuable data from tissues including cell phenotypes, densities and spatial biology. Our expertise in running commercially validated assays in addition to developing custom algorithms allows us to extract the information that matters for your clinical programs
Image Analysis Capabilities
Our team of scientists is always available for consultation to help make sense of the expansive datasets generated for your trials.
Our team at Reveal Biosciences, a company acquired by CellCarta, specializes in the generation of customized Machine Learning/Artificial Intelligence (ML/AI)-based digital assays.
Reveal’s digital pathology services, powered by the imageDx™ software platform, transforms tissue biology into actionable data across all therapeutic areas. The imageDx™platform supports a wide range of data inputs including whole slide images, genomic data, spatial data, and more. Model development is driven by machine learning and a full suite of image annotation tools that characterize tissue features, regions of interest, cell types, and staining across tissue sections.
Take your data even further with predictive AI, utilizing the power of deep learning to predict responders, stratify patient groups, and predict treatment outcomes. Flexible assay outputs and data visualization tools including heatmaps allow for fully optimized end-to-end AI models to be deployed globally in the cloud.
CellCarta is also offering AI algorithm development services using HALO® AI software. HALO® AI utilizes advanced deep learning neural network algorithms and allows training by example with advanced cell segmentation and tissue classification tools.