The best scientific minds working together to advance precision medicine
If you are passionate about science, join CellCarta and help shape the future of precision medicine.
As a global Contract Research Organization Laboratory (CRO) to the biopharmaceutical industry, CellCarta provides access to a broad offering of biomarker platforms and services. We partner with you to address the most complex scientific testing needs, delivering customized biomarker testing solutions to further the limitless potential of precision medicine.
CellCarta, which is under the private ownership of Arsenal Capital, is the union of scientific pioneers of the CRO industry supporting discovery, translational and clinical research. At the core of CellCarta is the fusion in 2019 of Caprion Biosciences and HistoGeneX which brought together a unique combination of biomarker expertise focused on immune monitoring, histopathology, proteomics and genomics, including the capabilities of previously acquired Primity Bio and Serametrix.
Leveraging its presence on four continents and through the addition of Clinical Logistics Inc. and Mosaic Laboratories, which further expanded its specimen logistics services and biomarker franchise, CellCarta is uniquely positioned to provide complex and customized clinical biomarker solutions at the global level.
At CellCarta, we understand that each individual is as unique and complex as a puzzle, an enigma waiting to be solved. Our scientists along with your team are on a journey of discovery, charting a course that leads to safer and more effective treatment solutions.
Our solutions are tailored to your needs and we always ensure that you benefit from our unparalleled scientific expertise at every stage of our collaboration with you.
Working as an extension of your lab, our team of scientists has an unwavering commitment to proactively partnering with you in developing your biomarker strategies, using the most rigorous scientific controls.
With us as your partner, you too will go further. With access to our 4 integrated technological platforms and our end-to-end sample management services, we will be there, supporting you throughout the entire drug development cycle, from discovery to all phases of clinical development.
Explore our global & integrated laboratory testing services:
Immune Monitoring: Multiplex assays for monitoring of immune responses to support clinical trials.
Histopathology: Multiplexed tissue analysis with in-house team of pathologists for biomarkers, clinical testing, and companion diagnostics
Proteomics: Fully integrated mass spectrometry platforms designed for large scale discovery studies and bioanalytical & clinical testing
Genomics: Proven and emerging molecular platforms for clinical sample analysis
Headquartered in Montreal (Canada), the company operates globally with over 700 employees in its nine facilities located in Canada, USA, Belgium, Australia, and China.
Chief Executive Officer
A co-founder of Caprion, Martin has for over 15 years led Caprion’s technology development, laboratory operations and commercial strategy focused on specialized laboratory research services in the fields of proteomics, immune monitoring, and personalized medicine. Profitable and rapidly growing based on its research contracts and strategic partnerships with over 75 global pharmaceutical and biotechnology companies, Caprion is also developing its own proprietary diagnostics tests for cancer, diabetes, and infectious diseases. Since 2007, Martin has concluded 3 company acquisitions and has successively managed Caprion under the ownership of 3 leading healthcare private equity firms, including the recent sale of Caprion to GHO Capital in July 2017.
Prior to Caprion, Martin began his professional career as a management consultant with McKinsey & Company. He then initiated his career as a biotech entrepreneur at Advanced Bioconcept, initially as Vice-President of Sales & Marketing and then as General Manager following the company’s acquisition by NEN Life Sciences (now part of Perkin-Elmer).
Martin is currently a member of the Board of Directors of Caprion, Softbox Systems, Mispro Biotech Services, Prevtec Microbia, Montreal InVivo, the Atlantic Cancer Research Institute and of the Centre for Commercialization of Cancer Immunotherapy. He is also a member of the Investment Committee of the Amorchem venture fund.
Martin earned his bachelor’s degree in Economics from the University of Moncton prior to completing an M.A. in Economics and Politics at Oxford University as a Rhodes Scholar.
President and Global Chief Operating Officer
Nick brings nearly 30 years of global business experience in healthcare services and products, scientific products, medical devices, and distribution. Nick joined Caprion in October 2020 as the President and Global Chief Operating Officer responsible for Global Laboratory and Commercial Strategy as well as the Information Technology and Human Resources functions of the global corporation. He is also responsible for ensuring the company has the adequate structure and processes in place to provide a platform for future growth.
Prior to joining Caprion, Nick has worked extensively for Baxter Healthcare, Fisher Scientific (now Thermo Fisher Scientific), and Covance (CRO). Having started his career in sales he has had roles of increasing responsibility in sales, marketing, business development, country management, regional general management, divisional operations and manufacturing, and global leadership. Most recently he was the CEO & President of a privately held clinical trial research site network in the US.
Nick earned undergraduate BS & BA degrees from Northwestern University, and MBA from the Kellogg School of Management.
Global Chief Financial Officer
Tony is a seasoned financial executive with a proven background leading teams in a variety of business environments including strategic growth and operating model transformations, business acquisitions, and turnarounds. He joined Caprion in October 2020 and oversees the finance, accounting, tax, treasury, and legal functions of the global corporation.
Prior to joining Caprion, Tony was Senior Vice President and CFO at Albany Molecular Research, Inc. – a GTCR/Carlyle Group portfolio CDMO. In this role, he had leadership responsibilities for all aspects of finance, accounting, tax, treasury, pricing, global information systems, lender relations, acquisitions/divestitures, and corporate strategy. He also shared responsibility for several enterprise-wide projects. Prior to this, Tony served as CFO for Bruker Corporation, a publicly traded global scientific instrumentation provider. He also held other finance executive roles with Merck KGaA, Millipore, and Gerber Scientific. In addition to his corporate finance roles, he has also served as an auditor at Price Waterhouse.
Tony holds a BS in accounting from Central Connecticut State University, an MBA from the University of Connecticut, and is a CPA.
Chief Regulatory and Government Affairs Officer
Todd joined Caprion in September 2020 as the leader of our quality, regulatory and government affairs team, overseeing the overall regulatory requirements on ISO, CAP /CLIA, GLP and GCLP, and assisting clients in defining their global regulatory pathways for their development and clinical programs.
Todd brings more than 26 years of combined experience in the biopharmaceutical, diagnostics, and food/nutrition businesses at Abbott. Todd has held a variety of technical and leadership roles in R&D, Operations, QA, and Regulatory Affairs. He has served on a number of boards and academic advisory positions including Regulatory Affairs Professional Society (RAPS), Lambs Farm, the International Life Sciences Institute, the Dean’s Advisory Board for the School of Pharmacy at Purdue University and as a Ford Scholar at Northwestern’s Kellogg School of Management.
Todd earned his bachelor’s degree in Pharmacy from Purdue University, a master’s degree in Engineering and Management Sciences from Northwestern University and a PhD in Pharmacy from the University of Illinois.
Senior Vice-President and Chief Financial Officer, Immunology & Proteomics
Normand joined Caprion in July 2014. He has global responsibility for leading finance functions for the company, with particular focus on supporting strategic growth initiatives by representing the company with potential investors and business partners. Normand brings a solid financial background, impressive executive leadership skills and a vast array of connections in the life sciences industry and investment community. Prior to Caprion, Normand held the position of President & CEO at Victhom Human Bionics, a publically-traded medical device company and previously was the Vice President Finance of MOXXI Medical, CFO of NSI Global Inc. and Speedware Corporation Ltd and as a Director of High Tech Financing at BNP Paribas.
Normand received his Master of Science Degree in International Finance from HEC Montreal and Bachelor of Business Administration in Finance from UQAM Montreal.
Senior Vice-President and Chief Operating Officer, Immunology & Proteomics
Lorella received her PhD in Biochemistry from the University of Montréal and is a well-respected executive in the CRO industry. Her scientific expertise includes assay development and validation using different types of platforms (mass spectrometry, immunoassays, flow cytometry, ELISpot, and others) for the analysis of biomarkers, as well as drug products. Dr. Di Donato has validated over 200 assays and was instrumental in the deployment of these assays from exploratory to primary endpoints, combining the technical and scientific aspects, along with the regulatory requirements. Dr. Di Donato has been actively involved in regulatory audits throughout her twenty years in the CRO industry. She is also a regular contributor and presenter at the WRIB, co-authoring many of the white papers. In addition,, Dr. Di Donato has been a speaker at several international conferences on proteomics for biomarkers and drug product quantitation.
Since 2012, Dr. Di Donato has led the scientific operations team at a global level at Caprion Biosciences (North American and Europe). She oversees immune monitoring, proteomics, bioinformatics, and project management, supporting drug development programs. Prior to joining Caprion, Dr. Di Donato was Vice-President, Research and Development at Cirion BioPharma Research, responsible for technology transfer, method development and validation of biomarker, PK, and immunogenicity assays.
Senior Vice-President and Chief Operating Officer, Histopathology & Genomics
Senior Vice-President and Chief Commercial Officer
Carol has over 25 years of executive management experience in the diagnostic, medical device, and biotechnology industry. Carol joined Caprion in January 2014 as the Chief Business Officer and Sr. Vice President responsible for the commercial strategy and activities related to business development, marketing, product development, and customer service.
Prior to joining Caprion, Carol served as the Senior Vice President and General Manager for Asuragen’s Genomic Services and CLIA Laboratory Division. From 2002 to 2007 Carol was a member of the senior management team at Ciphergen Biosystems Inc., a proteomic equipment and pharmacoproteomic research company. At Ciphergen she was responsible for diagnostic business development, sales and marketing, and assessing new potential diagnostic discoveries viable for commercialization. Carol served as the Vice President of Sales/Marketing for Dynacare Laboratories for three years where she was instrumental in expanding Dynacare’s market share to a national ranking through acquisitions, strategic partnerships with hospitals, and organic sales growth nationwide. Carol started her diagnostic career at Roche Biomedical Laboratories where she was one of the top fifty General Managers from 1986 to 1996.
Carol received her Bachelor of Science Degree from Texas A&M University where she was a four-year Letterman on the Women’s Golf Team. She received her MBA-Information Technology Degree from University of Dallas in 2004.
Senior Vice-President and Corporate Development Officer
Patrick joined the Caprion team in 2011. He is a biopharmaceutical and investment executive with broad expertise in R&D and business development. He is leading the corporate strategies and the development of innovative diagnostics based on proteomic discoveries made at Caprion for indications such as cancer, as well as metabolic and infectious diseases.
Prior to joining Caprion, Patrick has worked with Pappas Ventures, a US-based venture capital firm that guided the development of more than 50 life science companies in therapeutics, diagnostics, medical devices, and personalized medicine. He held positions as Vice-President of R&D at BioAxone and as Director of Pharmacology at Neurochem where he developed neuroprotective and neuroregenerative drugs for Alzheimer’s disease and spinal cord injury. He was also Assistant Professor in Neurology at the University of California in San Francisco where he worked on neurodegenerative diseases induced by prions and was part of the Nobel Laureate Team of Stanley Prusiner, Medicine and Physiology (1997).
Patrick has been involved in many innovative life science initiatives. He is one of the co-founders of the Personalized Medicine Partnership for Cancer and was intimately involved in the creation and financing of the new Neomed Institute. In recent years, he has held numerous advisory positions with diverse organizations such as the Campus des Technologies de la Santé, Quebec Consortium for Drug Discovery, Centre of Excellence for Commercialization and Research of the Montreal Neurological Institute, and at Pharmacology Institute of Sherbrooke University. He is presently a member of the Board of Directors of Univalor.
Patrick holds a BSc degree in Microbiology and Immunology from McGill University and a PhD in Molecular Biology from the University of Montreal. He has also completed post-doctoral studies at the Max Planck Institute for Biophysical Chemistry in Germany.
Chief Medical & Scientific Officer
Dr. Mark Kockx founded HistoGenex Laboratories in 2001. At the University of Antwerp, Belgium, Dr. Kockx pioneered methodologies to elucidate apoptotic and cytostatic response of cancer patients after treatments with targeted therapies. His subsequent collaborations with global pharmaceutical companies led to the founding of Histogenex Laboratories.
Dr. Kockx is an internationally recognized pathologist-scientist who has operated on the forefront of personalized medicine developments. He continues to lead initiatives to standardize biomarker analysis practices in addition to adapting novel technologies. Dr. Kockx has been extensively involved with the clinical trials that led to the approval of well-known targeted therapies such as EGFR, BRAF and MEK inhibitors. His current passions are two fold. He is introducing practices and workflows for next generation IHC, combining innovations of multiplex staining, quantification and image capture. He has also developed an Immunomics program, a state of the art biomarker program that supports the evolving and numerous needs of immunotherapy development.
Senior Vice-President and Chief Financial Officer, Histopathology & Genomics
Dr. Dirk Hendriks is a co-founder of HistoGeneX. In addition to serving as the financial officer and directing the strategic business development at HistoGeneX, Dr. Hendriks is a clinical pathologist and professor of Medical Biochemistry at the University of Antwerp in Belgium. He maintains an active lecturing schedule covering medical biochemistry, clinical pathology and laboratory management courses. In his university group, prof. Hendriks studies the development of new fibrinolytic mechanisms and drugs for the treatment of thrombo-embolic diseases.
His business experience includes extensive deal-structuring collaborations with the pharmaceutical Industry and also with strategic vendors. Previously, Dr. Hendriks has also successfully founded clinical pathology laboratories in the Antwerp area with subsequent mergers and acquisition transactions of these entities.
Senior Vice-President and Chief Business Officer
Mr. Christopher Ung has served in the companion diagnostics field since its inception and is one of the original pioneers of the personalized medicine field. He led the global commercialization efforts of the HercepTest™ and pharmDx EGFR companion diagnostic assays and continues to lead and implement global biomarker strategies for drug development projects. He has established several global companion diagnostic partnerships that have played a pivotal role in targeted therapy development and has set up CAP, CLIA laboratories in the US, Scotland, China, and Singapore.
Mr. Ung leads the development and execution of HistoGeneX’s strategic and business initiatives, leveraging the company’s solid tumor and anatomic pathology services. Prior to joining HistoGeneX, he was Vice President of Strategic Business & Operations at Quintiles, Chief Operating Officer for Targeted Molecular Diagnostics and Chairman of the Pathology Business Group at DAKO.
Chairman of the BoardOperating Partner, Arsenal Capital Partners
Senior Partner, Arsenal Capital Partners
Investment Partner, Arsenal Capital Partners
Advisory Board Chairman & Senior Advisor, Arsenal Capital PartnersNobel Laureate
Senior Advisor & Advisory Board Member, Arsenal Capital Partners
Senior Advisor & Advisory Board Member, Arsenal Capital Partners
Chief Executive Officer, CellCarta
Senior Vice-President and Chief Financial Officer, Histopathology & Genomics, CellCarta
Chief Medical & Scientific Officer, CellCarta
Chairman of Arsenal Capital Partners Healthcare Advisory Board
Dr. Rothman is the Sterling Professor of Cell Biology and Chair of the Department of Cell Biology at Yale University School of Medicine. His research discoveries have been recognized by the Nobel Prize in Physiology or Medicine in 2013, the Albert Lasker Award and the Kavli Prize for Neuroscience. Dr. Rothman has been elected to membership in the National Academy of Sciences and its Institute of Medicine. Previously, he served as Chief Scientist of General Electric Healthcare and has served on the advisory boards of Amersham PLC, Johnson & Johnson Scientific, and Merck Scientific. Dr. Rothman graduated with a B.A. from Yale College, attended Harvard Medical School and received a Ph.D. from Harvard University. He has previously been a professor at Stanford, Princeton, and Columbia Universities and at Memorial Sloan- Kettering Cancer Center, where he served as Vice Chairman of the Sloan-Kettering Institute.
23rd Commissioner of the FDA
Dr. Gottlieb is a physician and served as the 23rd Commissioner of the U.S. Food and Drug Administration. Dr. Gottlieb’s work focuses on advancing public health through developing and implementing innovative approaches to improve medical outcomes, reshape healthcare delivery, and expand consumer choice and safety. He is currently a partner at the venture capital firm New Enterprise Associates; a resident fellow at the American Enterprise Institute; a contributor to CNBC; and a board member to Pfizer, Inc. and Illumina, Inc.
Under his leadership, the FDA advanced new frameworks for the safe and effective oversight of gene therapies, cell-based regenerative medicines, targeted drugs, digital health devices, and vaccine manufacturing. The agency implemented new reforms to standardize drug reviews and make historic improvements of post-market data collection and the use of real-world evidence. He promoted policies to reduce death and disease from tobacco, improve food innovation and safety, and aggressively confront addiction crises. The agency’s historic and prolific advances in new policy distinguished his tenure as the FDA’s commissioner, in addition to a record-setting number of approvals of novel drugs, medical devices, and generic medicines.
Previously, Dr. Gottlieb served as the FDA’s Deputy Commissioner for Medical and Scientific Affairs and before that, as a Senior Adviser to the Administrator of the Centers for Medicare and Medicaid Services, where he helped advance policies to improve healthcare quality and promote the effective use of new medical technologies. Dr. Gottlieb was a practicing hospitalist and a Clinical Assistant Professor at the New York University School of Medicine. He is an elected member of the National Academy of Medicine.
Department of Microbiology and Immunology, Stanford University
Dr. Nolan is the Rachford and Carlota A. Harris Professor in the Department of Microbiology and Immunology at Stanford University School of Medicine. He trained with Leonard Herzenberg (for his PhD) and Nobelist Dr. David Baltimore (for postdoctoral work on the first cloning/characterization of NF-κB p65/RelA and the development of 293T rapid retroviral production systems). He has published over 200 research papers, holds 17 US patents and has been honored as one of the top 25 inventors at Stanford University. He has trained more than 30 graduate students and 40 postdoctoral or clinical fellows. Dr. Nolan’s areas of research include hematopoiesis, cancer and leukemia, autoimmunity and inflammation, and computational approaches for network and systems immunology. His most recent efforts are focused on a single cell analysis advance using a mass spectrometry-flow cytometry hybrid device, called CyTOF. The approach uses an advanced ion plasma source to determine the levels of tagged reagents bound to cells—enabling a vast increase in the number of parameters that can be measured per cell. Another recent innovation is termed molecular ion beam imaging (MIBI), a system that also uses mass tags that will enable sub-light imaging (5 nm resolution) of tissue sections with 50 or more parameters per image. His laboratory has already begun a large-scale mapping of the hematopoietic hierarchy in healthy human bone marrow at an unprecedented level of detail. A large focus of his lab is the development and utilization of machine learning algorithms to interpret the large high-dimensional datasets being produced by CyTOF and MIBI. Dr. Nolan’s efforts are to enable a deeper understanding not only of normal immune function, trauma, and other inflammatory events but also detailed substructures of leukemias and solid cancers—which will enable wholly new understandings, permitting better management of disease and clinical outcomes.
Department of Pathology, Case Western Reserve University
Dr. Sekaly is the Richard J. Fasenmyer Professor of Immunopathogenesis at the Case Western Reserve University School of Medicine, Director of the Center for Systems Immunology, and member of the Hematopoietic and Immune Cancer Biology Program at the Case Western Comprehensive Cancer Center. Dr. Sekaly’s lab has been focused for the past 20 years on developing a better understanding of the human immune response to vaccines and to chronic viral infections, with a specific focus on cancer and HIV infection. Over the past 7 years, Dr. Sekaly and his team have implemented the use of system biology approaches to monitor the diversity of memory T cells and to identify the mechanisms underlying it. His group has also pioneered the application of systems biology approaches to the understanding of mechanisms of action of the licensed vaccines and adjuvants, and has shown for the first time the diversity of the mechanism that lead to the establishment and persistence of different memory T cell subsets. Dr. Sekaly’s work has led to more than 342 peer-reviewed articles in scientific journals and more than 23 patents. He has been a principal investigator on numerous grants from the National Institutes of Health and foundations, including the Bill and Melinda Gates Foundation and the American Foundation for AIDS Research.
Senior Vice President for Experimental Therapeutics and Director, Sarcoma Center, Dana-Farber Cancer Institute; Professor and Co-Director, Ludwig Center at Harvard
George Demetri, MD, FASCO has dedicated his career to translational research aimed at understanding and treating precisely-defined subsets of cancers. He was a pioneer in the development of imatinib (Gleevec®), the first cancer therapy targeting gastrointestinal stromal tumor (GIST) as a molecularly defined subset of sarcoma. Subsequently, his work has contributed to the U.S. FDA and worldwide regulatory approvals of several other “smart drugs” for cancer, including sunitinib (Sutent®) and regorafenib (Stivarga®) for GIST, tazemetostat (Tazverik®) for epithelioid sarcomas, as well as pazopanib (Votrient®) and trabectedin (Yondelis®) for other sarcomas. In a related contribution, Dr. Demetri served on the Scientific Advisory Board for Plexxikon to help develop the first mutant BRAF inhibitor, vemurafenib (Zelboraf®), a mutation-targeted therapy for a subset of melanomas. Most recently, he helped starting Blueprint Medicines in Cambridge, MA, which recently announced the U.S. FDA approval of avapritinib (Ayvakit®) for a mutationally-defined subset of GIST.
He received his undergraduate degree in Biochemistry from Harvard College, then was a research fellow at the Universite of Besancon, France before receiving his medical degree from Stanford University School of Medicine. Subsequently, he completed his residency and became Chief Residency in Internal Medicine at the University of Washington Medical Center in Seattle before training as a fellow in Medical Oncology at the Dana-Farber Cancer Institute and Harvard Medical School, where he has served as an Attending Physician since 1989.
Dr. Demetri is a Professor of Medicine at the Harvard Medical School (HMS), where he is co-Director of the Ludwig Center at Harvard and a co-director of the HMS post-graduate course entitled “High Impact Cancer Research: Cancer Biology and Therapeutics”. He also teaches a Harvard College Freshman Seminar on the Scientific, Ethical and Humanistic Aspects of Cancer. He has served on the Board of Directors of the American Association for Cancer Research (AACR) and now chairs the AACR Science Policy and Government Affairs Committee. Dr. Demetri was a founding director of the annual AACR special workshop on Translational Cancer Research for the Basic Scientist. He also serves as a member of the Board of Directors for Blueprint Medicines and Translate Bio, both in Cambridge Massachusetts.
Professor of Genitourinary Oncology, Barts Cancer Institute
Dr. Powles is a Clinical Professor of Genitourinary Oncology and the lead for solid tumor research at Barts Cancer Institute in the United Kingdom. His work focuses on a spectrum of clinical studies from Phase I to randomized Phase III, with the majority of the studies being translational Phase II investigating novel targeted and immune therapies. Alongside these trials, Dr. Powles’ research focuses on correlation of novel biomarkers and aims to define markers that are of prognostic value and can predict response or resistance to therapy. Dr. Powles has written in over 100 peer review papers in this area and has received grant income from national and international funding bodies. He graduated from St. Bartholomew’s Medical School, London in 1996, and completed his post-graduate training in oncology in 2005, receiving an MD from the University of London in 2006.
Investigator, Howard Hughes Medical Institute; Marie-Josée and Henry Kravis Chair in Human Oncology and Pathogenesis; Chairman, Human Oncology and Pathogenesis Program
Charles L. Sawyers received a BA from Princeton University in 1981 and an MD from Johns Hopkins University School of Medicine in 1985, and completed his internal medicine residency at UCSF. He became a Howard Hughes Medical Institute Investigator in 2002 while at UCLA, and then moved to the Memorial Sloan Kettering Cancer Center in 2006 where he currently serves as the Chair of the Human Oncology and Pathogenesis Program.
Sawyers studies mechanisms of cancer drug resistance with an eye toward developing novel therapies. He co-discovered the antiandrogen drug enzalutamide (Xtandi®) that was approved by the FDA in 2012 for treatment of advanced prostate cancer. He shared the 2009 Lasker-DeBakey Clinical Medical Research Award for the development of the ABL kinase inhibitor imatinib for patients with chronic myeloid leukemia and the second generation ABL inhibitor dasatinib to overcome imatinib resistance. He received the 2013 Breakthrough Prize in Life Sciences, the 2013 Taubman Prize for Excellence in Translational Medical Science and the 2015 BBVA Knowledge Award in Biomedicine.
Sawyers is a member of the National Academy of Sciences, the National Academy of Medicine (formerly IOM) and the American Academy of Arts and Sciences. He is past President of the American Association for Cancer Research (AACR) and the American Society of Clinical Investigation (ASCI), was appointed to the National Cancer Advisory Board by President Obama and has served on the Board of Directors of Novartis since 2013. He also serves as Steering Committee Chair of the AACR Project GENIE, an international consortium of cancer centers who share genomic and clinical data from patients treated at their respective clinical sites.
Chief, Immuno-Oncology Service, Human Oncology and Pathogenesis Program Memorial Sloan Kettering Cancer Center
Jedd Wolchok is Chief of the Immuno-Oncology Service and holds The Lloyd J. Old Chair in Clinical Investigation at Memorial Sloan Kettering Cancer Center, Associate Director of the Ludwig Center for Cancer Immunotherapy and Director of the Parker Institute for Cancer Immunotherapy at MSK. Dr. Wolchok is a clinician-scientist exploring innovative immunotherapeutic strategies in laboratory models, and a principal investigator in numerous pivotal clinical trials. He specializes in the treatment of melanoma. The focus of his translational research laboratory is to investigate innovative means to modulate the immune response to cancer as well as to better understand the mechanistic basis for sensitivity and resistance to currently available immunotherapies.
Director of the Center for Cellular Immunotherapies, University of Pennsylvania
Carl June is the Richard W. Vague Professor in Immunotherapy in the Department of Pathology and Laboratory Medicine. He is currently Director of the Center for Cellular Immunotherapies at the Perelman School of Medicine, and Director of the Parker Institute for Cancer Immunotherapy at the University of Pennsylvania. He is a graduate of the Naval Academy in Annapolis, and Baylor College of Medicine in Houston, 1979. He received his graduate training in immunology and malaria with Dr. Paul-Henri Lambert at the World Health Organization, Geneva, Switzerland from 1978-79, and his post-doctoral training in transplantation biology with E. Donnell Thomas and John Hansen at the Fred Hutchinson Cancer Research Center in Seattle from 1983 – 1986. He is board certified in Internal Medicine and Medical Oncology. He maintains a research laboratory that studies various mechanisms of lymphocyte activation that relate to immune tolerance and adoptive immunotherapy for cancer and chronic infection. In 2011, his research team published findings detailing a new therapy in which patients with refractory and relapsed chronic lymphocytic leukemia were treated with genetically engineered versions of their own T cells. The treatment has now been used with promising results to treat children with refractory acute lymphoblastic leukemia. He has published more than 350 manuscripts and is the recipient of numerous prizes and honors, including election to the Institute of Medicine in 2012 and the American Academy of Arts and Sciences in 2014, the William B Coley award, the Richard V Smalley Memorial Award from the Society for Immunotherapy of Cancer, the AACR-CRI Lloyd J. Old Award in Cancer Immunology, the Philadelphia Award in 2012, the Taubman Prize for Excellence in Translational Medical Science in 2014 (shared w S. Grupp, B. Levine, D. Porter), the Paul Ehrlich and Ludwig Darmstaedter Prize (shared w J. Allison), the Novartis Prize in Immunology (shared w Z. Eshaar and S. Rosenberg), the Karl Landsteiner Memorial award, the Debrecen Award and a lifetime achievement award from the Leukemia and Lymphoma Society.
CellCarta has a deep understanding of the regulatory requirements critical to the success of its partners and is committed to providing the highest quality every step of the way.
We were inspected and accredited for specific CAP and CLIA tests by the College of American Pathologists. We also welcome and host multiple sponsor audits to ensure sponsor requirements are met and opportunities for improvement are identified.
If you are passionate about science, join CellCarta and help shape the future of precision medicine.