Flow cytometry is an established technology for the phenotypical and functional analyses at the single cell level.
At CellCarta, we harness the potential of multiparametric flow cytometry and work closely with you to deliver both qualitative and quantitative analyses of samples.
Keeping up with the evolution of the technology, we offer multiple platforms, including spectral flow (CYTEK Aurora), and an advanced multiparametric analysis expertise to bring valuable insight to your data.
Our services are provided in a GCLP environment and our laboratories have CAP accreditations and are CLIA-certified, providing rigorous quality assurance oversight.
We offer flow cytometry services in North America, Europe, China, and Australia, to align with the global needs of your clinical studies. Our flow cytometry platforms can generate data for exploratory, secondary, or primary endpoints.
Our multiparametric cytometry analysis expertise includes spectral flow. With its capabilities to detect up to 40 parameters and its higher flow rate, the CYTEK Aurora allows for a high-throughput ideal for clinical samples. Learn more about it from our flow cytometry expert!
Both off-the-shelf and customized panels are available for your studies. Our flow cytometry experts guide you towards the right panel, so you get the most insight from your samples and achieve your objectives through all phases of clinical development.
Our scientists are experts in both flow cytometry and immunology, which ensures you are properly advised during assay design, study planning, methodology, data analysis and reporting.
Beyond our expertise with flow technology, we analyze and share large dimension data sets using CellEngine, our own cloud-based data analysis software. The CellEngine software can automatically tailor gates with its built-in supervised autogating tool.
Our skilled team can provide guidance on optimal sample stability and logistics management, including PBMC processing for high quality samples.
We work with all types of samples and offer in-house sample procurement, preparation, stimulation, or stabilization if needed.
We conduct robust, GCLP-compliant assay validations that are detailed in a comprehensive and customized report and accompanied by a Quality Assurance Compliance Statement for results you can be confident in.
Mock runs and panel qualifications are performed to evaluate sample integrity and inter- and intra-assay variability before initiating any experiment.
Our flow cytometry platform allows you to identify, quantify, and monitor your cell population of interest as well as its functional activity using off-the-shelf or highly customized panels.
The following services can be used to study your cell populations/subsets at steady state or following treatment and/or stimulation:Cell Enumeration Cellular Phenotyping – Intra-cellular and surface profiling Cellular Proliferation and Cell Cycling Cell Sorting (FACS) – Isolate your subset of interest MDSC Assays – Follow the expression of myeloid-derived suppressor cells Receptor Occupancy (RO) - Assess the binding characteristics of therapeutics Phosphoflow – Map your pathway by monitoring phosphorylation status in cells Degranulation (BAT) – Measure basophil degranulation Intracellular Cytokine Staining (ICS) - Monitoring cytokine production Multimer Staining Assay – Test antigen-specific responses