Alternative Name(s): Programmed Cell Death 1 Ligand 1, PDCD1, B7-H1, CD274 Antigen, Systemic Lupus Erythematosus Susceptibility 2 (SLEB2)
Test Description
Programmed cell death 1 ligand 1 (PD-L1) is a member of the B7 family of cell surface ligands that regulate T cell activation and immune responses. The PD-L1 ligand binds the PD-1 transmembrane receptor and inhibits T cell activation. The PD-L1 assay using clone SP263 is a companion diagnostic for Durvalumab therapy.