Alternative Name(s): CHGA, Parathyroid Secretory Protein, Pituitary Secretory Protein, SP-I, Betagranin, Pancreastanin, Chromofungin, Catestatin, Vasostatin, Parastatin
Test Description
Chromogranin A is a commonly-used marker of neuroendocrine cells and tumors with neuroendocrine differentiation. Most small cell lung carcinoma (SCLC) cells demonstrate a cytoplasmic subcellular localization staining pattern, while most non-small cell lung carcinoma (NSCLC) cells are not as immunoreactive.