Alternative Name(s): pAKT, Phosphorylated Akt1, Protein Kinase B (PKB), AKT serine/threonine kinase 1
Test Description
The Akt protein family, also called protein kinase B (PKB), plays an important role in cellular survival pathways by inhibiting apoptotic processes and is one of the major downstream targets of the phosphatidylinositol 3 kinase (PI3K) pathway. Mammalian target of rapamycin (mTOR) is a key kinase acting downstream of the activation of PI3K.