Alternative Name(s): Cluster of Differentiation 11b, ITGAM, CR-3 Alpha Chain

CD11b_IHC

Test Description

CD11b, also known as integrin alpha M (ITGAM), is a protein subunit that forms a heterodimer with cluster of differentiation 18 (CD18). CD11b is expressed on the surface of leukocytes in the innate immune system including monocytes, natural killer cells, macrophages, granulocytes, and neutrophils and plays an important role in the adhesion and migration of cells to mediate the inflammatory response.