Test Description

Desmin is a muscle-specific type III intermediate filament that is essential for proper muscular structure and function. The protein plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils. Desmin can serve as a screening marker for neoplasms with myogenic differentiation including rhabdomyosarcoma, rhabdomyoma, leiomyosarcoma, leiomyoma, and others.