Alternative Name(s): Cathepsin G like 1, CTLA1, Fragmentin 2, T-Cell Serine Protease 1-3E, Cytotoxic T-Lymphocyte Proteinase 2
Test Description
Granzyme B (GZMB) is a serine protease most commonly found in the granules of cytotoxic lymphocytes (CTLs), natural killer cells (NK cells), and cytotoxic T cells. It is secreted by these cells along with the pore forming protein perforin to mediate apoptosis in target cells.