Alternative Name(s): MutS Homolog 6, GTMBP, P160


Test Description

The MSH6 gene on chromosome 2 is part of the DNA mismatch repair system. It encodes a component of the MutS family of proteins that are involved in DNA mismatch repair, and it heterodimerizes with MSH2 to form the MutS alpha complex, which serves as a bidirectional molecular switch for the mismatch repair machinery.