Alternative Name(s): Paired Box 5, BSAP, B-Cell Lineage Specific Activator


Test Description

Paired Box 5 (PAX-5) is a nuclear transcription factor expressed primarily in lymphocytes of the B cell lineage. PAX-5 is diagnostically useful and is expressed in Hodgkin lymphoma, diffuse large B-cell lymphoma, small B-cell lymphoma, B-lymphoblastic leukemia/lymphoma, and mixed phenotype acute leukemia with B-cell lineage.