Alternative Name(s): Prostate-Specific Membrane Antigen, FOLH1, Glutamate Carboxypeptidase 2
Test Description
Prostate-specific membrane antigen (PSMA) is a unique membrane bound glycoprotein overexpressed in prostate cancer. Overexpression in the vasculature of solid tumors has also been investigated. Conway et al. demonstrated that PSMA is required for angiogenesis and is essential for endothelial cell invasion.