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Precision Medicine Leader Caprion-HistoGeneX Rebrands as CellCarta

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Caprion Biosciences and HistoGeneX Unite

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Genomic Data Analysis

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Caprion-HistoGeneX expands its histological biomarker franchise by joining forces with Mosaic Laboratories

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Barts Cancer Institute and HistoGeneX Published Novel Research in Nature Medicine

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Navigating IVDR and Its Impact on Your Clinical Trial Assays

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Caprion Biosciences Offers Mass Cytometry CRO Services

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Caprion-HistoGeneX and Viroclinics-DDL announce a strategic partnership to advance infectious disease research

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Pathway Mapping

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Caprion-HistoGeneX acquires
Clinical Logistics Inc. - A virtual central specimen management CRO

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Discussing MHC Peptide Analysis with Eustache Paramithiotis

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Comprehensive Genomic Profiling with TSO500

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More Than Just Contaminants: The Two Sides of Cell Doublets in Flow Cytometry Data

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Caprion-HistoGeneX is offering molecular COVID-19 testing services while expanding its biomarker capabilities

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Measure Target Engagement With Receptor Occupancy Assays by Flow Cytometry

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CellCarta Expands its Biomarker Capabilities for Clinical Trials by adding Olink Technology to its Global Services

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physIQ and CellCarta Collaborate to Accelerate a More Precise, Personalized Approach to Vaccine Development

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Why drug development needs spatial biology

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Caprion Acquires Serametrix

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Spectral Flow and Mass Cytometry: Select the Right Platform for Your Clinical Study

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Targeted Protein Degraders

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Receptor Occupancy (RO) Assays

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Caprion Biosciences Leads Biomaker Validation AAPS Workshop

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The role of cytokine profiling in a changing cell therapy testing landscape

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How can HLA typing drive better immunotherapy development and selection?

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CellCarta PD-L1 IHC & Digital Pathology: BluePrint & Beyond

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CellCarta expands it proteomics portfolio with the acquisition of next-generation immuno-MRM assays from Precision Assays

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RNA Sequencing Services

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Simcere Diagnostics and CellCarta Enter Into Strategic Partnership

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Roche Presented Caprion Biosciencesā€™ Data on Clinical Proteomics Using Targeted Mass Spec

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Global Sample Processing Network

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Landmark study on metastatic breast cancer highlights the importance of identifying HER2-low patients

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Optimizing your in situ hybridization for success

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Immunogenicity and Safety of a Quadrivalent Plant-derived Virus Like Particle Influenza Vaccine Candidate - Two Randomized Phase II Clinical Trials in 18 to 49 and ā‰„50 Years Old Adults

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A Plant-Derived Quadrivalent Virus Like Particle Influenza Vaccine Induces Cross-Reactive Antibody and T Cell Response in Healthy Adults

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ICS and ELISpot for The Study of Cell Response: Choosing the Optimal Method in Immuno-Oncology or COVID-19 Vaccination Trials

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Final Results of Neoadjuvant Atezolizumab in Cisplatin-ineligible Patients with Muscle-invasive Urothelial Cancer of the Bladder

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Fibroblast Activation Protein-a and the Immune Landscape: Unraveling T1 Nonā€“muscle-invasive Bladder Cancer Progression

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B-cell maturation antigen (BCMA)

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How cell therapy developers are future-proofing clinical monitoring of B-cell aplasia

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Caprion-HistoGeneX is now CellCarta

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How to ensure consistent flow cytometry readouts between labs and optimize your clinical trials

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Intracellular cytokine staining (ICS)

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CellCartaā€™s HALO AI global deployment set to supercharge quantitative image analysis offering

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Ella™: Next-generation, automated ELISA multiplexing

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Antigen Presentation ā€“ A critical step for development of immune therapies

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Bioinformatics and Biostatistics

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Cellular Proliferation and Cell Cycling

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COVID-19 Clinical Testing for Drug Development

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Receptor Occupancy Assays - Bioanalytical Solutions

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Regulation-Compliant Flow Cytometry Analysis With CellEngine™

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Fast, Metadata-Driven Analysis and Visualization of Flow and Mass Cytometry Data with CellEngine™

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Our Laboratory in Jining, China

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How new approaches to VCN and cell enumeration are optimizing cell therapy clinical testing

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Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy

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Why HLA typing matters when evaluating novel cell therapies

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A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

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How Does Interim Sample Storage Improve Clinical Trial Outcomes?

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NanoString™

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Why Labs Should Use Spectral Flow Cytometry

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CellCarta Launches Advanced AI-Powered Spatial Biology Data for Clinical Trials

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Demystifying HGRAC ā€“ A Must When Running Clinical Trials in China

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OCT 2024

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RareCyte

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Precision Oncology Approaches: Using Proteomics to Build Next-Gen Diagnostic Solutions

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Infectious Diseases

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A comprehensive atlas of immunological differences between humans, mice and non-human primates

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Clinically Relevant Biomarkers in FFPE

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The Right Biomarker Strategy to Support Multiple Myeloma Emerging Therapies

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Leveraging Automatic Gating Tools in CellEngine for Easier, Faster Analysis

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CellEngineĀ® Software

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Optimal FFPE Tissue Fixation, Processing, and Embedding: A Comprehensive Guide

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What steps to follow when developing multiplex IHC assays

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Monitoring MDSC ā€“ A Hurdle to Immune Checkpoints Inhibitors

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Compensation Matters, But How Often?

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NEOEPITOPE DIRECT™

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Cell Therapy

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ESMO

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Simplify Cytometry Analysis with Easy, Customized Autogating Using CellEngine™

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CellEngine™: Transitioning to the Next Generation of Cytometry Analysis Software

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Letā€™s Talk: A Conversation with Former FDA Commissioner Scott Gottlieb

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Sample Management and Logistics

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Should Assessing T-Cell Response Be an Essential Part of COVID-19 Vaccine Development?

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OlinkĀ® PEA Technology

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Surface Profiling

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Preferential inhibition of adaptive immune system dynamics by glucocorticoids in patients after acute surgical trauma

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VoPo leverages cellular heterogeneity for predictive modeling of single-cell data

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New CellCarta Chinese Mobile Website and WeChat Mini-Program

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AACR ANNUAL MEETING 2024

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WRIB 2024

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CYTO 2024

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Our Histopathology Laboratories

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Navigating IVDR: Challenges and Strategies for Clinical Trial Assay Development and Regulatory Submissions

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Cellular Phenotyping

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Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial

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Towards a Personalized Assessment of Pancreatic Function in Diabetes

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Digital pathology in immuno-oncology ā€“ a roadmap for clinical development

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Influenza Virus-Like Particle Vaccines Made in Nicotiana Benthamiana Elicit Durable, Poly-Functional and Cross-Reactive T Cell Responses to Influenza HA Antigens

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The Mycobacterium tuberculosis regulatory network and hypoxia

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Industrialized MS-based Proteomics in the Search for Circulating Biomarkers

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Protein Biomarker Quantification by Mass Spectrometry

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An Integrated Multi-omic Single-Cell Atlas of Human B Cell Identity

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Single-Cell Profiling of Ebola Virus Disease InĀ Vivo Reveals Viral and Host Dynamics

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Single-cell metabolic profiling of human cytotoxic T cells

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Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front

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Subjects at-risk for future development of rheumatoid arthritis demonstrate a PAD4-and TLR-dependent enhanced histone H3 citrullination and proinflammatory cytokine production in CD14hi monocytes

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Challenges & Perspectives of Immunotherapy Biomarkers & The HistoOncoImmune™ Methodology

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Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles

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Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129

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ISCT 2024

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Tumor-specific MHC class II upregulation associated with response to anti-PD-L1 therapy in patients with urothelial cancer

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Characterization of Two Kinase-Modulating Compounds in Tumor Infiltrating Lymphocytes (TILs) Using Flow Cytometry and Meso Scale Discovery

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High Dimensional Flow Cytometry for Comprehensive Immune Monitoring of Vaccine Clinical Trials

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High Dimensional Flow Cytometry for Comprehensive Immune Monitoring in Clinical Trials

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Immunogenicity Assessment

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COVID-19 Outbreak Update

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Applications of Digital PCR in Clinical Research

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Seroconversion stages COVID19 into distinct pathophysiological states

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Landscape of coordinated immune responses to H1N1 challenge in humans

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Differential Dynamics of the Maternal Immune System in Healthy Pregnancy and Preeclampsia

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Variation of immune cell responses in humans reveals sex-specific coordinated signaling across cell types

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Flexible analysis of digital PCR experiments using generalized linear mixed models

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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

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The need for more holistic immune profiling in next-generation SARS-CoV-2 vaccine trials

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ALK

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HGF

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Phospho-GSK3b (Ser9/21)

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Clinical Proteomics

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Comparison of baricitinib, upadacitinib, and tofacitinib mediated regulation of cytokine signaling in human leukocyte subpopulations

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Circulating tumor cell detection: A prospective comparison between CellSearchĀ® and RareCyteĀ® platforms in patients with progressive metastatic breast cancer

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Seeing the Whole Picture: A Comparative Analysis of Digital Pathology Whole Slide Scanners

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Deployment of a visualization tool directly linked to CellEngine cytometry analysis software to accelerate analysis of complex cytometry data sets in the context of ongoing clinical trials

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Multi-Site Instrument Alignment Using Lyophilized BD™ CompBeads

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Predicting Immune Checkpoint Inhibitor Response Directly from Tumor RNA-Sequencing Data

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Antigen AtlasTM Database

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Multi-disciplinary Measurement of Host Biomarkers & Correlates in Infection and Immunity

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Untangle the complexities of TPD clinical development with expert biomarker services

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Let's Talk: A Conversation with CAR T-cell Therapy Pioneer Dr. Carl June

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Fit for Purpose GLP Validation of an Intra-Cellular Staining Assay

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Flow Cytometry Assay Validation as a Biomarker Versus in a Drug Development Setting

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Fit-for-Purpose GLP Validation of an Intra-Cellular Cytokine Staining Assay, ICI Boston

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Fit-for-Purpose GLP Validation of an Intra-Cellular Cytokine Staining Assay, CYTO

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Stability Assessment of Various Flow Cytometry Markers in Stabilized Whole Blood

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BCL6

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CD138

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Fucosyl-GM1

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A Quantitative Mass Spectrometry Workflow for Highly Multiplexed Measurement of Immunomodulatory Proteins to Support Immunotherapy Clinical Trials

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Multiple Myeloma Flow Cytometry Panel Validated for Clinical Monitoring of Patients

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Let's Talk: A Conversation with Dr. Scott Gottlieb

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Newsletter

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ISH

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Discover our laboratory in Jining, China

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Biomarkers UK 2024

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Webcast: A Conversation with CAR T-Cell Therapy Pioneer Dr. Carl June

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Analyzing multimodal single cell sequencing data like an Immunologist with hierarchical gating in CellEngine software

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World CB and CDx

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Biomarkers EU

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Basophil Activation Test (BAT)

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Immunology

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Lab Hacks: Inspiring Innovation in Cytometry Through Open Collaboration

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Patient Stratification using Clinical Proteomics ā€“ Validated multiplexed MRM assays to quantify HER2 and other biomarkers in clinical FFPE tissues

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Quantitative PCR

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FASN

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HLA-DP, DQ, DR (MHCII)

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MLH1

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panCK

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Proof-of-concept study to enumerate large oncosomes using the RareCyte CTC platform

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ASGCT 2024

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Discovery Phase

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Biologic Manufacturing

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High Throughput Automated Workflow for the Analysis of MHC-I and MHC-II Samples by LC-MS/MS

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MS-Based HCP Identification and Quantitation for Drug Substance Analysis

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Absolute Quantitation of Biotherapeutic Drug Product and Endogenous Protein in Human Serum Using a Hybrid Immunoassay-LC/MS Approach

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Absolute Quantitation of Five Antibody Drug Products in Dosed Monkey Serum, CSF and Brain Lysate for Lead Candidate Identification Using LC-MRM/MS

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Measurement of Protein X by LC-MRM/MS Using the AQUA Approach in Dissected FFPE Breast and Gastric Tumor Tissue

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Fit-for-Purpose Validation for the Measurement of 29 Cytokines in Human Plasma by MesoScale

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An LC-MRM/MS-Based PD Assay for Monitoring Site Occupancy of an Oncogene Protein in Tumor Xenograft Tissue from Mice Dosed with Alkylating Agent

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Cross Instrument Standardization: A Cornerstone of Measurement Assurance

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Patient-specific Immunophenotypic Aberrant Profiles Observed during Longitudinal Clinical Trials

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Successful Monitoring of Checkpoint Inhibitors By Flow Cytometry, AACR

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Successful Monitoring of Checkpoint Inhibitors By Flow Cytometry, SITC

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PD-1-Positive Population in Resting T Cells Identified Using a Qualified Flow Cytometric Method

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Mass Spectrometry Platforms for High Coverage Process-Specific Host Cell Protein Identification and Quantitation

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Patient-specific Fluorescence Aberration Profiles during Longitudinal Clinical Trials

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Protein Biomarkers Predictive of Multivalent Response to a Novel Dengue Vaccine

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Characterization of Two Potential Immunotherapeutics in Tumor Infiltrating Lymphocytes (TILs) Using Flow Cytometry and Meso Scale Discovery

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Acute febrile illness surveillance in a malaria endemic region of Madagascar: biomarker discovery for differentiation of bacterial and viral illnesses

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Case Studies: Atypical, Patient-Specific Profiles During Longitudinal Clinical Trials

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PD-1-Positive Population in Resting T Cells Identified Using a Qualified Flow Cytometric Method

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Extension of whole blood sample stability for flow cytometry analysis through the use of specialized blood collection tubes

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Multiplexed Mass Spectrometry Assay Identifies Neurodegeneration Biomarkers in CSF

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Development of an Absolute Quantitation Assay for Simultaneous Measurement of 9 Proteins From Cell Lysates by MRM

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Direct Identification of Neo-Epitopes in Tumor Tissue

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Investigating the proteome and phosphoproteome of renal cell carcinoma and the effect of delayed times to tissue fixation for FFPE and frozen samples

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Biomarker Discovery in Cerebrospinal Fluid for Schizophrenia and Antipsychotic Drug Treatment-Induced Weight Gain

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Development of a Mass Spectrometry Based Pharmacokinetic (PK) Assay for the Measurement of RLIP76 Protein and Proteoliposome in Human Serum

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Evaluation of a Multiplexed Mass Spectrometry-Based Method for Measuring Candidate Peptide Biomarkers in Alzheimerā€™s Disease Neuroimaging Initiative (ADNI) CSF

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Impact of Human Blood Specimen Collection, Manipulation, and Storage on Protein Integrity and Implications for Use in Clinical Research

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Discovery of a putative blood-based protein signature associated with response to ALK tyrosine kinase inhibition

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Biomarker recommendation for PDā€1/PDā€L1 immunotherapy development in pediatric cancer based on digital image analysis of PDā€L1 and immune cells

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Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

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Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2019 Conference Workshops

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Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops

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Metaproteomic and 16S rRNA Gene Sequencing Analysis of the Infant Fecal Microbiome

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Flow Cytometry Method Validation Protocols

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Humoral and Cell-Mediated Immune Responses to H5N1 Plant-Made Virus-Like Particle Vaccine Are Differentially Impacted by Alum and GLA-SE Adjuvants in a Phase 2 Clinical Trial

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ICCS/ESCCA Consensus Guidelines to detect GPI-deficient cells in Paroxysmal Nocturnal Hemoglobinuria (PNH) and related Disorders Part 4 ā€“ Assay Validation and Quality Assurance

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Identification of Host Proteins Predictive of Early Stage Mycobacterium tuberculosis Infection

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Analytical validation of protein biomarkers for risk of spontaneous preterm birth

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Recommendations for the Development and Validation of Flow Cytometry-Based Receptor Occupancy Assays

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Receptor Occupancy by Flow Cytometry

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Saturation Monitoring of VX15/2503, a Novel Semaphorin 4D-specific Antibody, in Clinical Trials

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Role of Receptor Occupancy Assays by Flow Cytometry in Drug Development

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Cdc42 and Rac1 Activity Is Reduced in Human Pheochromocytoma and Correlates With FARP1 and ARHGEF1 Expression

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A Signature for Immune Response Correlates With HCV Treatment Outcome in Caucasian Subjects

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Host Protein Biomarkers Identify Active Tuberculosis in HIV Uninfected and Co-infected Individuals

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Development and Evaluation of a Multiplexed Mass Spectrometry-Based Assay for Measuring Candidate Peptide Biomarkers in Alzheimerā€™s Disease Neuroimaging Initiative (ADNI) CSF

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PD-1 Coinhibitory Signals: The Link Between Pathogenesis and Protection

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CD160 Isoforms and Regulation of CD4 and CD8 T-cell Responses

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Validation of Cell-Based Fluorescence Assays: Practice Guidelines From the ICSH and ICCS - Part V - Assay Performance Criteria

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Proprotein convertase subtilisin/kexin type 9 (PCSK9) can mediate degradation of the low density lipoprotein receptor-related protein 1 (LRP-1)

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CD160 and PD-1 Co-Expression on HIV-Specific CD8 T Cells Defines a Subset with Advanced Dysfunction

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Proteomics-based confirmation of protein expression and correction of annotation errors in the Brucella abortus genome

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Modulation of the Phagosome Proteome by Interferon-Ī³

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Organ Messenger Ribonucleic Acid and Plasma Proteome Changes in the Adjuvant-Induced Arthritis Model: Responses to Disease Induction and Therapy With the Estrogen Receptor-Beta Selective Agonist ERB-041

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Immunopeptidomic Data Integration to Artificial Neural Networks Enhances
Protein-Drug Immunogenicity Prediction

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Clinical Proteomics for Patient Stratification - A GCLP Quantitative Mass Spectrometry Workflow for Multiplexed Measurement of Protein Biomarkers in FFPE Tissues (FFPE)

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Evaluation and implementation of an automated fluidic instability clean-up tool

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MDSC: Inhibiting Immune Therapy

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Biomarkers associated with ALT flares in HBsAg decline in patients with chronic hepatitis B

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Soluble plasma HLA peptidome as a potential source for CHB biomarkers

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Metaproteomic analysis of the infant fecal microbiome

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Obtaining CAP/CLIA Accreditation in a Canadian Clinical CRO - Challenges and Successes

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Case Study: Identification and Monitoring of Problematic HCPs for Improved Process Development

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Best practices for the development, analytical validation and clinical implementation of flow cytometric methods for chimeric antigen receptor T cell analyses

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Development and validation of a high-parameter mass cytometry workflow to decipher immunomodulatory changes in celiac disease

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Preclinical and clinical biomarker studies of CT1812:
A novel approach to Alzheimerā€™s disease modification

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Microenvironmental regulation of tumour immunity and response to immunotherapy

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Cellular Immunity, the key to your vaccineā€™s success

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Sample Logistics & Kitting Solutions

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Experts in Sample Logistics Solutions

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Wide Array of Services in Multiple Myeloma

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Quantification of sBCMA in Human Plasma using a High-Throughput Hybrid IP-MRM Based Mass Spectrometry Workflow

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Oncology & Immuno-Oncology Expertise

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Minimum Information for Publication of Quantitative Digital PCR Experiments

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Quality control of digital PCR assays and platforms

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The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

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AKT

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CAIX (CA9)

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CD1a

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CD3

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CD45

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Chromogranin A

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Claudin-18

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COX2

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Cyclin D1

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ERCC1

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HLA-DR

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HLA-E

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Ki67

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LAG3

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MSH2

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Nectin-2 (CD112/PVRL2)

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PD-L1 (73-10)

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p21

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p27

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panTRK

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PD-L1 (28-8)

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PD-L1 (SP263)

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PD-L1 (SP142)

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PD-L1 (E1L3N)

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Phospho-PRAS40 (Thr246)

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PI3K p110alpha

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Phospho-KAP-1

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PMS2

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PRAS40

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Vaccinia

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Discovery and validation of a serum microRNA signature to characterize oligo- and polymetastatic prostate cancer: not ready for prime time

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Plasma miRNAs as biomarkers for endometriosis

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Thank you for your interest!

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False positivity in break apart fluorescence in-situ hybridization due to polyploidy

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Accurately Predict Immune Checkpoint Inhibition Response Using Only RNA-Seq Data

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Immuno-MRM Assays

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Olink has arrived in China!

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Immuno UK 2024

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Exploiting tumor RNA-sequencing data for prediction of immune checkpoint inhibition response

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Genomic Assay List

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ASCO 2024

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M-Protein Analysis in Plasma of Multiple Myeloma Patients by Intact Mass Spectrometry

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How CellEngine Transforms Clinical Data Workflows with LIMS Integration

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